Single Emulsion Droplets - Microfluidic Starter Pack
This setup represents a simple solution for the generation of water-in-oil or oil-in-water droplets in single emulsion. The Starter Pack includes a complete equipment that allows you to create droplets through a microfluidic chip. We provide all the components you need for the droplet generation in your laboratory: syringe pumps, tubing, connectors and droplet generator chips.
Droplet generation finds applications in many scientific fields. Based on the emulsion of two immiscible liquids, this technique requires high precision and accuracy for applications in the pharmaceutical, cosmetic and food industries.
Microfluidics represents a rapid way to create highly monodispersed bubbles and droplets. We propose chips of great quality for the production of micro-sized droplets. The geometry of the intersection where the two phases meet, flow rates and fluid properties (surface tension, viscosity) determine local stresses which deform the liquid interface and lead to the production of drops. The drops are formed at the intersection of two immiscible fluids streams. Physically, the influence of the interfacial tension between the two phases governed by Rayleigh-Plateau instability enables the formation of drops. Finally, the application of a shear stress on an emulsion droplet causes its elongation, then its rupture.
Figure 1. Schematic illustration of the flow focusing geometry. Nooranidoost et al., Phys. Fluids 28, 123102 (2016)
We provide a complete equipment to produce droplets, particles or emulsions by using aqueous, organic, inorganic or fluorinated liquids:
- Syringe Pump (x2)
- Microfluidic chips
The pack can be used to generate droplets ranging in size from 30 to 200 µm through water in oil (w/o) or oil in water (o/w) emulsions.
The starter pack represents a basic and easy-to-use solution for researchers who wants to begin working with microfluidics in a simple and cost-effective way.
This setup includes two InfusionONE Syringe Pumps to control the flow of the two immiscible liquids independently.
Each syringe pump can hold 1 syringe from micro-liter sizes up to 140 mL and ensures reproducible flow rates. Infusion rates vary from 0.73 µL/hr (1 mL syringe) to 1500 mL/hr (60 mL syringe).
The pack includes a kit of 10x Luer Lock Plastic Syringes with different available sizes: 1 mL, 3 mL, 5 mL, 10 mL, 20 mL, 30 mL, 50 mL and 140 mL. Choose the kit according to your specific needs.
We offer a wide selection of off-the-shelf chips for the generation of droplets with different diameters. Choose between:
Polycarbonate Chips - mini Luer ports
Three chips made in PC are included in the pack. PC is a slightly hydrophobic thermoplastic polymer compatible with aqueous solutions (including diluted acids and bases), alcohols, oils and fats. These droplet generator chips have several inlets and outlets and one channel to fit all your experiments. They are available in two versions with different input channel widths for the production of droplets with two possible droplet diameters:
- Ø range 50 µm - 90 µm
- Ø range 110 µm - 170 µm
PDMS Chip - 1/16" (1.5 mm) ports
As alternative, one chip made in PDMS can come with the pack. PDMS is an hydrophobic elastomeric polymer and has ideal properties such as nontoxicity, biocompatibility, blood compatibility, elasticity, transparency, and durability. This droplet generator chip combines 11 devices in a standard microscope slide to create monodisperse emulsions. The diameter of droplets produced by each devices is:
- Ø range 20 µm - 40 µm
Glass Chip - 1/4"-28 UNF threaded ports
Another choice can be one chip made in glass. The glass ensures very high chemical and physical stability with the use of several solvents. This chip can generate a wide range of droplets sizes: use the first cross section to make small droplets, or the second cross section to make larger ones. You only have to plug the port you don't want to use. With one chip you can create droplet with two different diameter ranges:
- Ø range 40 µm - 60 µm
- Ø range 150 µm - 250 µm
Each microfluidic chip requires specific connectors and tubing. No problem, we provide all you need to complete the setup and generate droplets out of the box.
Connectors and tubing for the Polycarbonate Chip
This chip has mini Luer ports and to ensure a leak-free junctions to the inlets ant outlets we provide:
- 10x mini Luer connectors for soft-walled tubing
- 10x mini Luer plugs to close the unused ports
- 15m of silicone tubing 1mm (OD) x 1 mm (wall thickness) and 10x Barbed Adapters for the Female Luer of the syringe.
Connectors and tubing for the PDMS ChipThis chip has 1/16" (1.5 mm) ports directly compatible with 1/16" OD rigid tubing. The pack comes with:
- 10m of PTFE (teflon) tubing coil 1/16" OD
- 5x Female Luer Adapters and 10x 1/4"-28 fittings + ferrules for 1/16" OD tubing to complete the setup and allow you to connect the rigid tubing to the syringe
Connectors and tubing for the Glass ChipThis chip has 1/4"-28 UNF threaded ports compatible with 1/4"-28 fittings. The pack includes:
- 10x 1/4"-28 fittings + ferrules for 1/16" OD tubing and 10m of PTFE (teflon) tubing coil 1/16" OD
- 5x Female Luer Adapters compatible with the 1/4"-28 fittings to complete the setup and allow you to connect the rigid tubing to the syringe
- 10x 1/4"-28 Flat-Bottom Plugs to close the unused port of the microfluidic chip according to the cross section of the chip you decide to use for the droplet generation
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