Fast temperature control for live cell imaging of biological samples

microfluidic imaging

Fast temperature control for live cell imaging of biological samples



Category: Microfluidic camera imaging

A microfluidic-based thermalization system to achieve ultrafast temperature regulation on your biological sample during live cell observations.


This system is the fastest temperature controller commercially available and seamlessly couples with both standard and inverted microscopes.

On Demand

Our specialized microfluidics team will gladly help you define your needs
A microfluidic-based thermalization system to achieve ultrafast temperature regulation on your biological sample during live cell observations.
This system is the fastest temperature controller commercially available and seamlessly couples with both standard and inverted microscopes.

A microfluidic heater/cooler for live cell imaging

The system is fully automated and allows to change temperature between 5 and 45 °C in a mere 10 s with just one click. Furthermore, the temperature controller automatically accounts for room temperature variations and it does not require adapters (e.g. objective collars).

Fast temperature control for live cell imaging of biological samples

Why choose a microfluidic temperature controller?

Thanks to microfluidics' unique features, this system achieves unmatched speed and precision during temperature switches. Furthermore, as the thermalization chamber does not interface with your sample, no shear stresses are induced to the latter.

Lab-on-a-chip technology allows the temperature controller to be flexible and modular, so that it can be tailored for your specific application. Indeed, the system can be declined into three different packs, namely: C. elegans, yeast and mammalian cell packs.

Which types of samples can this be used on?

Currently, the microfluidic temperature control is optimized for studies on nematodes. The possibility to control the temperature so minutely opens a new world of possibile applications for your C. elegans researches. For example, temperature shocks have been shown to induce the depolymerization of the C. elegans embryo cytoskeleton (see figure below).

Fast temperature control for live cell imaging of biological samples

The flexibility given by microfluidics allows the temperature controller to be adapted to other types of samples as well. Configurations designed for yeast and mammalian cells are already available. 

Overview of the product: what's in the box?

Fast temperature control for live cell imaging of biological samples

Seamless integration with your microscopy setup

We know how crowded can become the surrounding of your microscope, that is why we propose a complete plug and play system which easily interface with your existing setup.

Fast temperature control for live cell imaging of biological samples

User-friendly software: your experiments are just a click away

The system comes with  a specific software developed with the user in mind. You just need one action to regulate the temperature of your sample during the experiment. Furthermore, the system automatically accounts for observations with immersed objectives and room temperature changes.

Fast temperature control for live cell imaging of biological samples 

Highlights

Speed: 10 s
Range: from 5 to 45 °C
Precision: 0.1 °C
Accuracy: 0.5 °C

Microfluidic temperature controller:

  • Temperature homogeneity: 0.5 °C
  • Absolute temperature precision: 0.1 °C
  • Absolute temperature accuracy: 0.5 °C
  • Range: from 5 °C to 45 °C
  • Maximum sample volume: 40 µl
  • Maximum sample height: 500 µm

Software:

  • Customized PID control for fastest yet accurate temperature switches
  • Room temperature monitoring for automatic corrections on the calibration
  • Chose between dry or immersion objective lens observations
  • Possibility to export measuring parameters to retrieve live temperature information

 

 

Software's system requirements:

  • USB 2.0 or faster connection
  • Intel pentium II 500 MHz or faster
  • 2 Gb of free disk space
  • Windows 7 and latest

Microfluidics contact team

Contact our team:

contact@darwin-microfluidics.com


Our specialized team is at your service to help you pick the product best suited to your needs. We also offer specific quotes for high quantity, specific, or custom orders. Feel free to ask, that's what we're for!