Microfiltration and Cell Isolation Chip - Complete Setup
Microfiltration and Cell Isolation Chip - Complete Setup
Microfiltration and Cell Isolation Chip - Complete Setup
Microfiltration and Cell Isolation Chip - Complete Setup
Microfiltration and Cell Isolation Chip - Complete Setup
Microfiltration and Cell Isolation Chip - Complete Setup
Microfiltration and Cell Isolation Chip - Complete Setup
Microfiltration and Cell Isolation Chip - Complete Setup
Microfiltration and Cell Isolation Chip - Complete Setup

Microfiltration and Cell Isolation Chip - Complete Setup

Available: In Stock
This modular microfluidic chip represents an innovative approach to create your own microfluidic platform for filtration and cell isolation. These chips were designed for reversible integration of various types of microfilters. The inlets and outlets with integrated Luer connections ensure leak-free junctions with the tubing and allow experiments under dynamic flow conditions.
The setup includes a Microfluidic Chip, a Clamp and a Microfilter! All you need to create your platform of microfiltration and cell isolation.
€300.00
This modular microfluidic chip represents an innovative approach to create your own microfluidic platform for filtration and cell isolation. These chips were designed for reversible integration of various types of microfilters. The inlets and outlets with integrated Luer connections ensure leak-free junctions with the tubing and allow experiments under dynamic flow conditions.
The setup includes a Microfluidic Chip, a Clamp and a Microfilter! All you need to create your platform of microfiltration and cell isolation.

Description

Three components characterize this microfluidic platform:

  • Microfluidic chip
  • Clamp
  • Microfilter

The modular microfluidic chip is designed for reversible integration of various types of filters and consists in two plastic plates in PC (Polycarbonate), each having four integrated magnets for reversible assembly and an elastomeric PDMS thin film to ensure good sealing up to pressures of 8 kPa. The Luer Connections in the upper part of the chip allow liquid perfusion and dynamic flow conditions during your experiments. The assembly is easy to use and with a reversible access to filter and isolated cells on chip for downstream analysis.

 

Benefits

  • Reversible patch integration thanks to the modular chip
  • Leak-free Luer Connection molded with the chip 
  • Highly-resistant and optically clear material
  • Standard microscope glass slide size

Setup

The microfluidic chip is available in three configurations:

a) Filter integration with tow connectors chip for trans- patch application, such as dead-end filtration or trans patch perfusion.
b) Filter integration with three connectors chip for trans- or cis- patch application, such as dead-end filtration, cross-flow filtration, etc.
c) Filter integration with four connectors chip for trans- or cis- patch application, such as dead-end filtration, cross-flow filtration, or air/liquid-liquid interface cell culture, etc.

When a filter is placed between the two plates, the force between the four pairs of magnets ensures auto-assembling at pressures up to 8 kPa. 

The clamp, included in the pack, ensures good sealing with high flow pressures (up to 100 kPa). The chip can be placed in a hand screwed clamp for assembling and fast operation. At the end of your experiment in dynamic flow conditions, the filter can be easily removed by dissembling the clamp and the microfluidic chip. 

 

Micro-engineered filters are available for high precision micro-particle or cell isolation. Unlike conventional filters, these filters are made of regular and high precision hole arrays realized by mass production. The shape, size and density of the holes are designed according to your specific needs. They can be used for the isolation of microorganisms, circulating tumor cells, fetal cells and endothelial progenitors in peripheral bloods.

The microholes can have different shape:

  • Funnel shape
  • Cylinder
  • Conical
The smallest diameter of the hole can be:
  • 6 μm
  • 5 μm
  • 1 μm (only for funnel shape)

Click here if you want to know more about the available microfilters!

 

Microfluidic chip 

Upper plate size 55 mm x 25 mm x 8 mm
Lower plate size 55 mm x 25 mm x 3 mm
Dimension for filter/patch chamber Φ 13 X 0.2 mm²
Channel width 1000 μm
Chamber depth 500 μm
Material PC with PDMS thin layer
Connection Luer connectors (2, 3 or 4)

 

Clamp 

Dimension  80 mm x 25 mm x 3 mm
Number of windows 1
Window size 40 mm x 20 mm x 3 mm
Material  Hard aluminum

 

Microfilter

Dimension Φ 13 X 0.2 mm²
Material PDMS

The Complete Setup includes:

  • 1x Microfluidic Chip with Luer Connectors
  • 1x Clamp
  • 1x Microfilter

    The setup comes sterile and have to be stored in dry conditions, without direct exposition to the sunlight at room temperature (15-25 °C).   

     

    Click here if you want to order Microfluidic ChipMicrofilters and Clamp separately!

     

    These chips are typically used for the integration a filter. Micro-chambers and micro-channels are predefined in both plastic plates to create a perfusable system when the setup is assembled.

    The principle of microfiltration can be used to isolate single cells from complex suspensions by using a continuous fluid flow through the microfluidic chip.

    Significative examples of filtration:

    • giant cell trapping
    • particle separation
    • animal or bacterial cell isolation

      Payment Terms

      You can either order and pay via credit card or invoice (through a purchase order). Please note that some products are not available for direct purchase: just click "Request a Quote" on the product page and fill in the form to get more informations!

      Credit card 

      • Add your products to the cart
      • In the cart page, click on Proceed to Checkout
      • Complete your credit card informations (don't worry, we are using Stripe, a PCI-certified program specialized in online transactions)
      • That's it! You will receive an order confirmation within a few minutes, and our team will send you the invoice.

      Invoice

      • Add your products to the cart
      • In the website header, click on Request a Quote
      • Fill in the required informations, then click on Submit Quote
      • Our team will send you a quote shortly
      • After receiving the quote, just send your purchase order at contact@darwin-microfluidics.com
      • Our team will complete your purchase and send you the invoice!

      A 25€ bank fee will be applied for any wire transfer in other currencies than Euros (€) outside the SEPA zone (European Union, Iceland, Norway, Liechtenstein, Switzerland, Monaco).

       

      Shipping

      The shipping charges are calculated based on the weight of the package and on the country of destination. We try to offer you the best shipping rates and services, shipping all our orders through UPS. Generally, your order reaches your lab in only 2 to 3 days after we send it, no matter the destination!

      Please note that our shipping incoterms are DAP (Delivered At Place). Please contact us if you prefer using your own courrier account or have any question!