Microfluidic Chip for Filter Integration - Luer
- Product SKU: MS-P1P-32-100
- Category: Cell Sorting / Trapping, MesoBioTech, Microfluidic Chips, Organ-on-a-chip Chips
This modular microfluidic chip represents an innovative approach to create your own microfluidic platform for filtration and cell sorting/trapping. This chips were designed for reversible integration of various types of microfilters, standard or custom-made. The inlets and outlets with integrated Luer connections ensure leak-free junctions with the tubing and allow experiments under dynamic flow conditions.
This modular microfluidic chip was designed for the reversible integration of various types of filters(to be ordered separately). The setup consists in two plastic plates in PC (Polycarbonate), each having four integrated magnets for reversible assembly and an elastomeric PDMS thin-film to ensure good sealing. The Luer connectors in the upper part of the chip allow liquid perfusion and dynamic flow conditions during your experiments. The assembly is easy to use and with a reversible access to the filter and cells for downstream analysis.
The microfluidic chip is available in three configurations:
a) Filter integration with two connectors for trans- patch application, such as dead-end filtration.
b) Filter integration with three connectors for trans- or cis- patch application, such as dead-end filtration, cross-flow filtration, etc.
c) Filter integration with four connectors for trans- or cis- patch application, such as dead-end filtration, cross-flow filtration, etc.
When a filter or patch is placed between the two plates, the force between the four pairs of magnets ensures auto-assembling at pressures up to 8 kPa.
To ensure good sealing with high flow pressures (up to 100 kPa), the chip can be placed in a hand screwed clamp (not included) for assembling and fast operation. At the end of your experiment in dynamic flow conditions, the filter or patch can be easily removed by dissembling the clamps and the microfluidic chip.
|Upper plate size||55 mm x 25 mm x 8 mm|
|Lower plate size||55 mm x 25 mm x 3 mm|
|Dimension for filter/patch insert||Φ 13 x 0.2 mm²|
|Channel width||1000 μm|
|Chamber depth||500 μm|
|Material||PC with PDMS thin layer|
|Connection||Luer connectors (2, 3 or 4)|
1x microfluidic chip for filter integration (configuration a, b or c)
The microfluidic chip comes sterile and has to be stored in dry conditions, without direct exposition to the sunlight at room temperature (15-25 °C).
These chips are typically used for patch and filter integration. Then, micro-chambers and micro-channels patterned in both plastic plates will ensure the correct fluid perfusion.
Significative examples of filtration:
- giant cell trapping
- animal or bacterial cell isolation
- particle separation
In the 4-Luer Connectors version, micro-chambers and micro-channels are patterned in both plastic plates of the chip to create two independent microfluidic systems: the upper and the lower chambers separated by the patch. These two microfluidic chambers can be perfused with different culture media.
When a tissue patch is placed between the two plates, culture media containing different factors can flow in the upper and lower chambers separated by the patch. Different tissue models such as skin, alveolar, stomach, brain-blood can be created.
- Reversible patch integration thanks to the modular chip
- Leak-free Luer Connection molded with the chip
- Highly-resistant and optically clear material
- Standard microscope glass slide size
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