Chip Micromixer - New Biocompatible Polymer

Microfluidic chip

Chip Micromixer - New Biocompatible Polymer



Category: Microfluidic chip, Micromixers Chips

Our new biocompatibe polymer technology is now brought to micromixers as an alternative to PDMS. The NPG72 polymer is biocompatible, cost-effective and its resolution can go down to 50 nm. Thanks to its self-sealing properties, leak-free connections have never been so easy.


Our micromixers are fully customizable to perfectly fit your experiments!


Exclusively on Darwin Microfluidics.

On Demand

Our specialized microfluidics team will gladly help you define your needs
Our new biocompatibe polymer technology is now brought to micromixers as an alternative to PDMS. The NPG72 polymer is biocompatible, cost-effective and its resolution can go down to 50 nm. Thanks to its self-sealing properties, leak-free connections have never been so easy.
Our micromixers are fully customizable to perfectly fit your experiments!
Exclusively on Darwin Microfluidics.

Features & Benefits

Unlike other mixing techniques, micromixers offer a convenient way to mix different fluids efficiently. They can be active when an external energy force is applied to mix the samples, or passive when the patterns of the microchannels are designed to increase the contact area and/or contact time between the samples. Then, the aim of microfluidic mixing is to achieve a thorough mixing within a shorter period of time, and in smaller microchannels to reduce the size of the chip. 

Compared to other chips, the NPG72 biocompatible properties and cost-effectiveness are a great asset for experiments. The NPG72 is biocompatible (certified ISO 10993-5 & UPS Class VI), and its self-sealing properties at ambient temperature is a great advantage for leak-free connections. This material is easy to use and doesn't tear apart like PDMS when manipulated.

We can advise you on a mixing design regarding your specifications.

Highlights:

  • Highly biocompatible material (ISO 10993-5 & UPS Class VI certifications)
  • Accurate and cost-effective: chips can be fabricated in a minute
  • Self-sealing at ambient temperature: no sealing step involving plasma, vacuum or high temperatures
  • Exclusively on Darwin Microfluidics
  • Packs of 1, 3 or 10 chips

 

Dimensions 75 mm x 25 mm
(standard microscope slide)
Material NPG72
Biocompatibility Yes (ISO 10993-5 & UPS Class VI)
Minimal microchannels width 50 nm
Microchannels depth range 50 nm - 1 mm
Inlet Multiple
Outlet 1
Inlet/outlet hole size 1 mm
Connection of outlets Standard 1/16" connection pads

 

    NPG72 polymer

    We chose NPG72 to give you the best products on the market. This new technology is at the dawn of the next microfluidic revolution, and is exclusively sold on Darwin Microfluidics.

    Advantages

    • Biocompatible: ISO 10993-5 & UPS Class VI certifications. No gloves or safety equipment needed to manipulate it.
    • No coating needed: the NPG72 can be easily functionalized
    • Compatible for optical assays: low fluorescence, optically clear.
    • No absorption, permeable to gas and not to liquid.
    • Versatile: Easy to connect with self-sealing pads for different tubing dimensions, no leakage unlike PDMS.
    • Cost-effective: Better performances than the current chips for a better price.
    • Resistant to tearing: Unlike PDMS, a NPG72 chip will not tear apart when you manipulate it. 
    • Convenient: Easily connect your chip with self-sealing connection pads. No leakage, no connection problem!
    • Accurate: Microchannels width down to 50 nm.

    Applications

    Several applications require a convenient way to model organs and dynamic cell cultures. The properties of the NPG72 offer solutions where PDMS could just give approximations.

    • Biochemistry analysis
    • Biomedical engineering
    • Pharmaceutical industry
    • Chemistry
    • ...

    The NPG72 offers a cost-effective solution to perform several assays.

     

    Contact us to set up together the perfect device for your needs! 

    Dimensions 75 mm x 25 mm
    (standard microscope slide)
    Material NPG72
    Minimal microchannels width 50 nm
    Microchannels depth range 50 nm - 1 mm
    Integration properties Any biological material
    Optical properties Optically clear
    Number of inlets Upon request
    Number of outlets 1
    Inlet/outlet hole size 1 mm
    Connection of outlets Standard 1/16" connection pads

     

    The micromixer design is adapted to the fluids which will be used. For example, the viscosity of the fluids is an important parameter to adjust the contact area between them, and then enhance the diffusive mixing effect.

    We can fabricate various mixing patterns. Contact us to find the best parameters.

    • How do I clean NPG72?

    Isopropyl alcohol, methanol, detergent solution or distilled water may be used. NPG72 has to be dry (air or oven dried) before molding to avoid bubbling or splays (cloudiness). Tape is also recommended to remove dust particles. We recommend working with NPG72 in a clean room or under a laminar hood to minimize particle contamination.

     

    • What is the most effective way to sterilize NPG72?

    Ethylene oxide, gamma irradiation, or autoclave will work. Please note that NPG72 products are not meant to be implanted in humans.

     

    • How do I create inlet and outlet holes for my microfluidic channels?

    Traditional biopsy punches used with silicones will not work here. The use of a rotary/hand punch or a laser cutter is recommended. Self-sealing connection pads have been developed and ensure easy and leak-free connections with any tubing.

     

    • Are NPG72-based microfluidic chips used for cell culture?

    While NPG72 is less permeable than PDMS, it still has sufficient air permeability to sustain certain cell cultures. NPG72 grades have successfully been used with yeast cells, NIH 3T3 fibroblasts, IPSCs (induced pluripotent stem cells), epicardium-derived cells, corneal cells, and other tumor cells.

     

    • What size range is reliably micromolded with NPG72?

    The minimal microchannel width is 50 nm, and the depth range is 50 nm-1 mm. However, microchannels between 5 µm and 1 mm are recommended with an aspect ratio (height to width) of 2:1 or less. Submicron structures and higher aspect ratios have also been achieved by some customers.


    Microfluidics contact team

    Contact our team:

    contact@darwin-microfluidics.com


    Our specialized team is at your service to help you pick the product best suited to your needs. We also offer specific quotes for high quantity, specific, or custom orders. Feel free to ask, that's what we're for!