NPG72 Polymer Starter Pack: alternative to PDMS

Microfabrication

NPG72 Polymer Starter Pack: alternative to PDMS



Category: Cell Culture Chips, Electrophoresis & Electrochemistry Chips, Microfabrication, Microfluidic Droplet Generators, Microfluidic Flow Cells, Microfluidic Organ-on-a-chip, Micromixers Chips

Try our brand new biocompatible polymer with this ready-to-fabricate start pack! The NPG72 is a great alternative to PDMS: self-sealing, resistant, cost-effective and biocompatible, it will greatly ease your work when fabricating chips. Contains 10 sheets of 15 x 15 cm NPG72 polymer.


Special discount this month! Save 50% off the regular price for this pack.

Availability: In Stock
€165.00
Try our brand new biocompatible polymer with this ready-to-fabricate start pack! The NPG72 is a great alternative to PDMS: self-sealing, resistant, cost-effective and biocompatible, it will greatly ease your work when fabricating chips. Contains 10 sheets of 15 x 15 cm NPG72 polymer.
Special discount this month! Save 50% off the regular price for this pack.

In this kit, you will be able to try the NPG72 with 10 sheets of 15 x 15 cm as an alternative to PDMS for your chip microfabrication. Different thicknesses are available upon request: 1.3 mm, 0.8 mm and 0.3 mm.

 

The NPG72 polymer is a real breakthrough for microfluidics

Features & Benefits

The NPG72 is a new polymer which gathers the advantages of PDMS without its drawbacks:

  • Biocompatible (ISO 10993-5 & UPS Class VI)
  • Self-sealing at ambient temperature: no need to use plasma bonding or high temperatures, you can then add biomaterials prior assembly
  • Cost-effective
  • Compatible for optical assays: low fluorescence, optically clear
  • No absorption, permeable to gas and not to liquid
  • Resistant to tearing: Unlike PDMS, it will not tear apart when you manipulate it

Effective integration, cellular and bio-reagents 

The high sealing performances of the NPG72 enable the integration of cells, proteins and others enzymes biomaterials prior to assembly. With a fabrication process that doesn’t involve plasma, vacuum or high-temperature, we can ensure that biological agents remain viable and functional in your device.

Fast microfabrication

  • Molding with a hot-embossing system
  • Low pressure: below 1 bar
  • No vacuum needed
  • Easy unmolding
  • Full operation takes less than a minute
  • Extremely low viscosity for rapid thermal molding with filling rates up to 100-1000 times greater than classical rigid thermoplastics (COC, PS, PMMA,…)

Applications

NPG72 is an alternative to any other chip material in the classical applications of microfluidic chips.

This polymer is particularly interesting in life sciences: its biocompatibility make it simple to design any experiment. The self-sealing technology is not destructive, unlike plasma, vacuum or high temperature used in the sealing of other chips.

Principal characteristics

NPG72 sheet dimensions 150 x 150 mm
Thickness 300 µm / 750 µm / 1.3 mm
Tear Strength 15 kN/m
Tensile Strength 7.6 kN/m
Elongation 720 %
Molding Temperature 115-185 °C

Self-sealing and fast bonding

The NPG72 is easy to bond to either NPG72 or glass after molding.

 

Bonding temperature NPG72 chip on NPG72 NPG72 chip on glass
Room temperature 600 mbar 400 mbar
85 °C 5.5 bar 720 mbar

 

 Contact us for more informations.

NPG72 sheet (x10): Available thicknesses of 1.3 mm, 0.8 mm and 0.3 mm. Dimensions of 15 x 15 cm.

  • How do I clean NPG72?

Isopropyl alcohol, methanol, detergent solution or distilled water may be used. NPG72 has to be dry (air or oven dried) before molding to avoid bubbling or splays (cloudiness). Tape is also recommended to remove dust particles. We recommend working with NPG72 in a clean room or under a laminar hood to minimize particle contamination.

 

  • What is the most effective way to sterilize NPG72?

Ethylene oxide, gamma irradiation, or autoclave will work. Please note that NPG72 products are not meant to be implanted in humans.

 

  • How do I create inlet and outlet holes for my microfluidic channels?

Traditional biopsy punches used with silicones will not work here. The use of a rotary/hand punch or a laser cutter is recommended. Self-sealing connection pads have been developed and ensure easy and leak-free connections with any tubing.

 

  • Are NPG72-based microfluidic chips used for cell culture?

While NPG72 is less permeable than PDMS, it still has sufficient air permeability to sustain certain cell cultures. NPG72 grades have successfully been used with yeast cells, NIH 3T3 fibroblasts, IPSCs (induced pluripotent stem cells), epicardium-derived cells, corneal cells, and other tumor cells.


Microfluidics contact team

Contact our team:

contact@darwin-microfluidics.com


Our specialized team is at your service to help you pick the product best suited to your needs. We also offer specific quotes for high quantity, specific, or custom orders. Feel free to ask, that's what we're for!