Bubble Trap for Microfluidics
Rated 3.5/5 based on 11 customer reviews

Bubble Trap for Microfluidics

A bubble trap to get rid of bubbles in your flow stream. Air bubbles in a liquid sample are a typical issue often found in microfluidic experiments, and their elimination in the sample is quite usually hard to achieve.
Available in 3 versions of internal volume 44 µL (S), 97 µL (M), and 320 µL (L).
Available immediately
€110.00
A bubble trap to get rid of bubbles in your flow stream. Air bubbles in a liquid sample are a typical issue often found in microfluidic experiments, and their elimination in the sample is quite usually hard to achieve.
Available in 3 versions of internal volume 44 µL (S), 97 µL (M), and 320 µL (L).

With this device, you can remove bubbles in your flow stream without any negative effect on the overall performance. Its principle relies on the pressure differential between the two sides of a hydrophobic PTFE membrane to remove bubbles from aqueous solutions.

  • Robust, chemically resistant, and biocompatible (PVC body & PTFE membranes)
  • Fitted to your volume needs 44µL (S) - 97µL (M) - 320 µL (L)
  • Flow rates from around 5 µL/min (indicative values)
  • Compatible with standard 1/4-28 fittings

We recommend using the bubble trap to avoid typical issues:

  • Biological sample damaging (cytotoxicity)
  • Sensors and chromatography columns drying
  • Bubble-induced shear stress
  • Volume sampling errors
  • Flow instabilities due to bubbles in droplet generation

Principle

This bubble trap features a PTFE membrane. The solution containing bubbles is pushed into the trap and the bubbles are removed through a micro-porous PTFE membrane in a leak-free manner. You can optionally connect a vacuum pump to the rear outlet of the trap (active mode) to increase the bubble trap performance. But the trap usually shows significant bubble trapping performance on most setups even if no pump is connected (passive mode).

The bubble trap can be used in two modes

This microfluidic bubble trap can be used in two modes: a passive mode, and an active mode where a vacuum line can be added. In this second mode, the vacuum outlet of a pressure generator, such as this microfluidic pressure controller, can be used to maximize the bubble trap’s efficiency. This bubble trap enables achieving 100% debubbling for a flow of up to 60 mL/min. This microfluidic bubble trap is typically used in the range of 0.5 - 2.0 mL/min, but up to 60 mL/min can be achieved when a vacuum line is used.

Passive Mode Active Mode
Schematic showing the active mode setup for bubble trapping with pressure controller



1x Bubble trap body (lower and upper part) in PVC

2x 1/4-28 fittings for 1/16" OD tubing + ferrules

1x M5 mounting screw

2x PTFE membranes

Body material PVC
Membrane material PTFE
Connection ports 1/4-28 UNF
Maximum operating pressure 2 bar (30 psi)
Dimensions (mounted) 30 x 30 mm cylinder
Flow range 5 µL/min up to 6 mL/min (more in active mode)1
Sterilization methods

Not autoclavable

70% ethanol cleaning

Internal volume

44 µL (small version)

97 µL (medium version)

320 µL (large version)

1 In some applications (very low flow rate or high flow rate), you may have to use an external vacuum source to increase the pressure differential between the two sides of the membrane to get a better debubbling efficiency. Use the 1/4-28 UNF air outlet to connect your vacuum source.

Important notes

• This version is not autoclavable
• Not for use with organic solvents, as it may result in leakage
• Always push liquids toward the trap as there is a risk of bubble generation if used the wrong way

  • Which parameters can I choose when selecting my bubble trap?

The internal volume of the bubble trap is the only parameter you can choose. We have three variants: 44 µL, 97 µL, and 320 µL.

  • Should I select my bubble trap based on the flow rate of my experiment?

The flow rate is not the principal parameter you should consider when selecting your bubble trap, as each variant of the device works for a large range of flow rates: researchers usually use it for flow rates up to 60 mL/min and down to 10 µL/min. However, the smaller the internal volume, the less efficient the bubble trap will be for higher flow rates (see graph in "Specifications").

  • Which internal volume should I choose, according to my experiment?

A higher internal volume will trap more of your solution inside the bubble trap, and this volume cannot be recovered in output. So if the solution you are using is precious, prefer a lower internal volume. Moreover, if your flow rate is really low, a smaller internal volume will help for the good work of the device. See the graph in "Specifications" for more information.

  • Which pressure should I apply if I use the bubble trap in active mode?

You can use the bubble trap either in passive or active mode. In active mode, we have tested it for up to 2 bar applied with a vacuum pump. Then, it all depends on your experiment: if only 0.5 bar is needed to remove the bubbles from your solution, then it is not useful to increase the vacuum pressure.

  • How should I clean my bubble trap?

You can clean your bubble trap with distilled water after each experiment but also with 70% ethanol if you work in sterile conditions: organic solvents can only damage the bubble trap if they are in contact during a long period, but it is suitable for a short cycle of cleaning. Do not forget to remove the membrane, clean it with ethanol and then flow water to remove ethanol traces. The bubble trap is not autoclavable since it is made of PVC, and it is not suitable for organic solvents.

  • How often should I change the membrane?

As soon as you see a decrease in its efficiency, you can change the membrane of your bubble trap. There is no theoretical duration of each membrane because it all depends on which conditions you use your device.

  • Can I use this bubble trap with living cells?

Of course! Many researchers use it, and we have never had any negative feedback.

Feel free to contact us for any additional questions!

Payment Terms

You can either order and pay via credit card or invoice (through a purchase order). Request a quote easily by clicking on the "Request a Quote" button in the cart page.

Please note that some products are not available for direct purchase: just click "Request a Quote" on the product page and fill in the form to get more informations!

Credit card 

  • Add your products to the cart
  • In the cart page, click on Proceed to Checkout
  • Complete your credit card informations (don't worry, we are using Stripe, a PCI-certified program specialized in online transactions)
  • That's it! You will receive an order confirmation within a few minutes, and our team will send you the invoice.

Invoice

  • Add your products to the cart
  • In the website header, click on Request a Quote
  • Fill in the required informations, then click on Submit Quote
  • Our team will send you a quote shortly
  • After receiving the quote, just send your purchase order at contact@darwin-microfluidics.com
  • Our team will complete your purchase and send you the invoice!

 

If you wish to pay in USD, GBP or AUD, please specify it in your PO. We can add the converted value in the required currency to the quote if requested.

 

Worldwide shipping

We ship worldwide from our warehouse in France.

Shipping charges are calculated based on the shipping country, and can be estimated from the cart page. Our shipping rates and times are:

  • France: GLS (1-2 business days), free shipping above 350€
  • Germany, Austria, Belgium, Denmark, Spain, Hungary, Italy, Luxembourg, Netherlands, Poland, Portugal, Czechia, Slovakia:
    • GLS (2-4 business days), free shipping above 350€
    • DHL Express (1-2 business days), reduced rate above 350€
  • Bulgaria, Croatia, Estonia, Finland, Ireland, Latvia, Lithuania, Romania, Slovenia, Sweden, Greece, Cyprus, Malta: DHL Express (1-2 business days), free shipping above 400€
  • United Kingdom: DHL Express (1-2 business days), free shipping above 400€
  • USA, Canada: DHL Express (1-3 business days), free shipping above 400€
  • Switzerland: DHL Express (1-2 days), free shipping above 450€
  • Other countries: DHL Express, shipping rates based on the destination, weight and dimensions

 

If you wish to use your own shipping account, we will charge a flat fee of 15€.

We reserve the right to apply a surcharge for parcels > 30 kg, palletized shipments, or packages with dimensions exceeding the maximum dimensions of our carriers.

Please note that our standard shipping incoterms are DAP (Delivered At Place), or EXW if using your own carrier.

Contact us if you have any questions!

Customer Reviews

Based on 8 reviews
100%
(8)
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T
Thomas

Darwin Microfluidics has a broad catalog for fluidics and flow chemistry applications. Moreover, products sold are of good quality and the delivery is fast.

A
Anna Damianopoulou
Good Service- and after sales-

Good Service- and after sales-

D
DONG HOON KANG

Write your comments here

L
Ludmila Abezgauz

Thank you for good service and quick delivery

O
Olayaa Maaijil

Bubble Trap for Microfluidics Kit

Customer Reviews

Based on 8 reviews
100%
(8)
0%
(0)
0%
(0)
0%
(0)
0%
(0)
T
Thomas

Darwin Microfluidics has a broad catalog for fluidics and flow chemistry applications. Moreover, products sold are of good quality and the delivery is fast.

A
Anna Damianopoulou
Good Service- and after sales-

Good Service- and after sales-

D
DONG HOON KANG

Write your comments here

L
Ludmila Abezgauz

Thank you for good service and quick delivery

O
Olayaa Maaijil

Bubble Trap for Microfluidics Kit