EXTENDO 944X
EXTENDO 944X Featuring several next gen optimizations, the Extendo 944X telehandler is powered by a standard
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EXTENDO 944X Featuring several next gen optimizations, the Extendo 944X telehandler is powered by a standard
EXTENDO 944X Featuring several next gen optimizations, the Extendo 944X telehandler is powered by a standard
EXTENDO 944X Featuring several next gen optimizations, the Extendo 944X telehandler is powered by a standard
EXTENDO 944X Featuring several next gen optimizations, the Extendo 944X telehandler is powered by a standard
EXTENDO 944X Featuring several next gen optimizations, the Extendo 944X telehandler is powered by a standard
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TAMARA is a microfluidic-based nanoparticle formulation system tailored for comprehensive research and development needs. It excels in nanoparticle formulation from initial screening through to in vitro and in vivo testing, managing volumes from 0.2 to 10 mL with exceptional repeatability. This allows consistent use throughout preclinical development without needing to reoptimize formulations.
Developed by microfluidic experts, TAMARA simplifies nanoparticle synthesis. Beginners can synthesize nanoparticles in under two minutes by setting formulation parameters, loading samples, and pressing run. The integrated interface easily manages synthesis conditions, saving and loading runs.
TAMARA supports all development phases with a single platform, transitioning smoothly from µL-scale screening to in vitro and in vivo testing. Its optimized design maximizes sample usage, even at very low volumes, minimizing losses.
Equipped with advanced microfluidic mixers, TAMARA offers a broad nanoparticle size range (50–400 nm), a Polydispersity Index (PDI) under 0.2, up to 97% encapsulation efficiency for RNA-LNP, and excellent batch-to-batch consistency (formulation dependant).
TAMARA works with most non-polar solvents and various nanoparticle types, including polymer-based, lipid, and hybrid nanoparticles, making it ideal for encapsulating a wide range of payloads, from RNA and DNA to small drugs and ASOs.
Designed for optimal cleanability and reusability, TAMARA minimizes cross-contamination with components like PEEK reservoirs and thermoplastic microfluidic chips, ensuring reliable results with easy cleaning and sterilization.
Note: The guaranteed outcome is for the first run only. Chip's reusability depends on formulation and target volume.
In summary, TAMARA is a versatile, easy-to-use platform for nanomedicine and LNP R&D, offering unparalleled control, repeatability, and application range, making it a valuable tool for researchers.
1x TAMARA Controller
1x TAMARA Module
1x Reservoir
20x Microfluidic chips
Dimensions | Controller: 31 x 34 x 36 cm / 12.2 x 13.4 x 14.2 in Synthesis module: 23 x 26 x 23 cm / 9.1 x 10.2 x 9.1 in |
Weight | Controller: 4.2 kg / 9.26 lbs Synthesis module: 3.8 kg / 8.38 lbs |
User Interface | Touchscreen (800*480 px) |
Electrical Power | 110-220 V / 36 W |
Gaz Pressure Input | 8 to 10 bars Only use dry and non-corrosive nor explosive gas |
Operating Temperature | 10 – 40°C |
Inlet Volumes | Depend on reservoir size |
Achievable Volumes | 0.2 - 10 mL |
Total Flow Rate (TFR) | 0.8 - 15 mL/min |
Flow Rate Ratio (FRR) Solvent:Water | 1:1 to 1:10 |
Initial Lipid Concentration Range | 1 to 10 mg/mL |
Chemical Compatibility | Any aqueous buffers & polar solvent compatible with the wetted materials (Topas/COC and PEEK – e.g ethanol, methanol, etc.). See Topas and PEEK chemical compatibility here. |
Material Loss | < 10% or 50 µL (whichever higher) |
Material | COC |
Designs | Herringbone and Baffled mixers |
Material | PEEK |
Volume | 0.2 - 3 mL or 1 - 30 mL (both can be combined) |
Nanoparticle Types | Polymer and lipid-based nanoparticles (PLGA, RNA-LNP, SLN, Liposomes, etc.) |
Payload* | All RNA types, DNA, small molecules, peptides |
Size Range* | 50 – 300 nm |
Batch to Batch Size Repeatability | < 3% |
PDI* | < 0.2% |
EE%* | Up to 97% with RNA-LNP |
*Formulation dependent
Darwin Microfluidics being based in France, ships orders under Delivered At Place (DAP) incoterms. This means that for customers outside the European Union (EU), you are responsible for any applicable customs fees, duties, and taxes in addition to the shipping costs. These charges are determined by your local customs authority and must be paid by you upon the arrival of the shipment in your country.
We recommend contacting your local customs office for detailed information on these charges if you're ordering from outside the EU, as they can vary depending on the destination and the value of your order. Please note that these additional costs are not included in the shipping fees charged by Darwin Microfluidics.
If you've received your order from Darwin Microfluidics and found that a product is defective or missing, please follow these steps to resolve the issue:
Report immediately: Contact our customer service team as soon as possible. Reporting the issue promptly helps us address your concern more efficiently.
Provide details: When you contact us, please provide your order number, the name the order was placed under, and a detailed description of the issue. For defective products, include clear photos or a video that shows the defect.
Review: Our team will review your claim to determine the best course of action. We may ask for additional information or details about the problem.
Resolution: Depending on the situation, we may send a replacement for the defective or missing item, provide a refund, or offer another satisfactory resolution. Our goal is to ensure you are completely satisfied with your purchase.
Follow-up: We will keep you updated throughout the process and confirm when the issue has been resolved to your satisfaction.
We apologize for any inconvenience caused by a defective or missing item and are committed to resolving your issue as quickly and smoothly as possible.
At Darwin Microfluidics, our goal is to offer the most competitive prices directly as our list price, ensuring that all our customers receive great value without needing to navigate complex discount structures. Here’s a detailed look at our discount policy:
Competitive list prices: We work hard to ensure our list prices are among the most competitive in the market. This approach allows us to offer fair pricing to all our customers from the start, eliminating the need for frequent discounts.
Quantity-based discounts: For certain products, we offer quantity-based discounts directly on the product pages. These discounts are automatically applied based on the quantity of the product you purchase, providing savings for bulk purchases without the need for special codes or negotiations.
Bulk orders: While we strive to offer the best prices upfront, we understand that customers making large-scale purchases may have special considerations. In such cases, we invite you to discuss your needs with our sales team. Depending on the size and nature of your order, we may be able to offer tailored discounts or pricing adjustments.
We believe in transparency and simplicity in pricing, allowing you to make your purchases with confidence, knowing you're receiving a fair deal without the hassle of negotiating discounts. If you have any questions about pricing or discounts for bulk orders, please don't hesitate to reach out to our sales team for personalized assistance.
Please follow our returns & refund page.
Once shipped, your order will typically arrive within 1-3 business days for standard shipping within continental North America and Europe, and 2-5 business days for international deliveries.
After placing your order, you'll receive a tracking number via email to monitor its progress. Please note, these times are estimates and may vary based on location and external factors.
At Darwin Microfluidics, we typically ship orders as a complete package once all items are ready. However, we understand that certain situations may require partial shipments. Upon request, we can accommodate partial shipments of your order.
Please be aware that an additional shipping fee may apply for this service. If you need part of your order shipped separately, please contact our customer service team to discuss your specific needs and any additional costs involved.
Since Darwin Microfluidics sells exclusively to companies and institutions and is based in France, the VAT treatment for your orders depends on the location of your company or institution:
Within the EU (excluding France): For customers in other EU countries, the reverse charge mechanism applies. This means that VAT is not charged by us at the point of sale. Instead, it is your responsibility to account for the VAT at the standard rate applicable in your country under the reverse charge procedure. This process helps simplify cross-border transactions within the EU.
In France: For customers located in France, standard French VAT rates apply to all purchases. As a France-based company, we are required to charge VAT on sales to other French companies and institutions, which you can then reclaim according to local VAT procedures if applicable.
Outside the EU: For customers outside the European Union, sales are not subject to VAT by us. However, you may be subject to import duties, taxes, and charges that are not included in the item price or shipping cost. These charges are the buyer's responsibility and vary by country. We advise checking with your local customs office for more information.
Please ensure your VAT identification number is provided during the ordering process for EU transactions to qualify for the reverse charge mechanism. If you have any questions regarding VAT charges or need further assistance with VAT-related issues, please contact our customer service team.
We are unable to provide specific estimates for customs fees, duties, or taxes associated with your order. These charges are determined by the customs authority in your country and can vary based on a variety of factors, including the type of items purchased, their value, and the country to which they are being shipped.
We recommend contacting your local customs office directly to get the most accurate and up-to-date information regarding potential customs charges for your order. They can provide you with detailed guidelines on the fees you might expect to pay based on the products you're importing from us.
Please remember, these charges are the responsibility of the recipient and are not included in the shipping costs paid to Darwin Microfluidics.
Got a question or need a custom microfluidic solution? Our experts are here to help! Whether you're looking for prototyping, design consultation, or bulk manufacturing, we provide tailored solutions to fit your needs.
Send RequestTAMARA is a microfluidic-based nanoparticle formulation system tailored for comprehensive research and development needs. It excels in nanoparticle formulation from initial screening through to in vitro and in vivo testing, managing volumes from 0.2 to 10 mL with exceptional repeatability. This allows consistent use throughout preclinical development without needing to reoptimize formulations.
Developed by microfluidic experts, TAMARA simplifies nanoparticle synthesis. Beginners can synthesize nanoparticles in under two minutes by setting formulation parameters, loading samples, and pressing run. The integrated interface easily manages synthesis conditions, saving and loading runs.
TAMARA supports all development phases with a single platform, transitioning smoothly from µL-scale screening to in vitro and in vivo testing. Its optimized design maximizes sample usage, even at very low volumes, minimizing losses.
Equipped with advanced microfluidic mixers, TAMARA offers a broad nanoparticle size range (50–400 nm), a Polydispersity Index (PDI) under 0.2, up to 97% encapsulation efficiency for RNA-LNP, and excellent batch-to-batch consistency (formulation dependant).
TAMARA works with most non-polar solvents and various nanoparticle types, including polymer-based, lipid, and hybrid nanoparticles, making it ideal for encapsulating a wide range of payloads, from RNA and DNA to small drugs and ASOs.
Designed for optimal cleanability and reusability, TAMARA minimizes cross-contamination with components like PEEK reservoirs and thermoplastic microfluidic chips, ensuring reliable results with easy cleaning and sterilization.
Note: The guaranteed outcome is for the first run only. Chip's reusability depends on formulation and target volume.
In summary, TAMARA is a versatile, easy-to-use platform for nanomedicine and LNP R&D, offering unparalleled control, repeatability, and application range, making it a valuable tool for researchers.
1x TAMARA Controller
1x TAMARA Module
1x Reservoir
20x Microfluidic chips
Dimensions | Controller: 31 x 34 x 36 cm / 12.2 x 13.4 x 14.2 in Synthesis module: 23 x 26 x 23 cm / 9.1 x 10.2 x 9.1 in |
Weight | Controller: 4.2 kg / 9.26 lbs Synthesis module: 3.8 kg / 8.38 lbs |
User Interface | Touchscreen (800*480 px) |
Electrical Power | 110-220 V / 36 W |
Gaz Pressure Input | 8 to 10 bars Only use dry and non-corrosive nor explosive gas |
Operating Temperature | 10 – 40°C |
Inlet Volumes | Depend on reservoir size |
Achievable Volumes | 0.2 - 10 mL |
Total Flow Rate (TFR) | 0.8 - 15 mL/min |
Flow Rate Ratio (FRR) Solvent:Water | 1:1 to 1:10 |
Initial Lipid Concentration Range | 1 to 10 mg/mL |
Chemical Compatibility | Any aqueous buffers & polar solvent compatible with the wetted materials (Topas/COC and PEEK – e.g ethanol, methanol, etc.). See Topas and PEEK chemical compatibility here. |
Material Loss | < 10% or 50 µL (whichever higher) |
Material | COC |
Designs | Herringbone and Baffled mixers |
Material | PEEK |
Volume | 0.2 - 3 mL or 1 - 30 mL (both can be combined) |
Nanoparticle Types | Polymer and lipid-based nanoparticles (PLGA, RNA-LNP, SLN, Liposomes, etc.) |
Payload* | All RNA types, DNA, small molecules, peptides |
Size Range* | 50 – 300 nm |
Batch to Batch Size Repeatability | < 3% |
PDI* | < 0.2% |
EE%* | Up to 97% with RNA-LNP |
*Formulation dependent
Tamara - application note: Liposomes synthesis and size characterization with high precision DLS
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EXTENDO 944X Featuring several next gen optimizations, the Extendo 944X telehandler is powered by a standard
EXTENDO 944X Featuring several next gen optimizations, the Extendo 944X telehandler is powered by a standard
EXTENDO 944X Featuring several next gen optimizations, the Extendo 944X telehandler is powered by a standard