Organ-on-a-Chip - Open Membrane Chip - Mini Luer
Rated 3.5/5 based on 11 customer reviews

Organ-on-a-Chip - Open Membrane Chip - Mini Luer

The Fluidic 219 Organ-on-a-Chip by Microfluidic ChipShop provides an affordable and compact method for replicating biological barriers in vitro. Each chip features four open culture chambers, allowing direct access to the membrane area.
The chip is fabricated in Topas (COC, cyclic olefin copolymer) for better light transmittance. The inlets and outlets with integrated Mini Luer connections ensure leak-free junctions with the tubing and allow experiments under dynamic flow conditions.
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€79.50
The Fluidic 219 Organ-on-a-Chip by Microfluidic ChipShop provides an affordable and compact method for replicating biological barriers in vitro. Each chip features four open culture chambers, allowing direct access to the membrane area.
The chip is fabricated in Topas (COC, cyclic olefin copolymer) for better light transmittance. The inlets and outlets with integrated Mini Luer connections ensure leak-free junctions with the tubing and allow experiments under dynamic flow conditions.

This Organ-on-a-Chip allows you to reliably mimic physiological conditions in vitro and study tissue organization, cell-cell interactions, barrier penetration, and physiological responses in a more in vivo-like environment.

These open chips have been designed to allow direct access to membrane areas and provide a permanent entry port for liquid supply, storage, and exchange.

This chip is designed to develop models of physiological barriers and to ensure an in vivo-like environment under static or dynamic flow conditions. Each chamber has 2 mini Luer connection ports to supply the bottom compartment, below the membrane. In combination with matching interaction tanks for liquid supply and storage, this chip allows for a wide variety of filtering and assay tasks.

The entire body of the chip is made of Topas, a cyclic olefin copolymer (COC) to overcome the limitations of standard PDMS. Topas does not unspecifically absorb medium contents and has high stability and ideal optical characteristics for the bright field as well as fluorescence microscopy. Topas is frequently used in medical devices due to its proven biocompatibility.

Each chamber offers an 8 µm porous membrane.

Features

  • Mini Luer connection molded with the chip: leak-free
  • Highly resistant and optically clear material: Topas (COC, cyclic olefin copolymer) has high transparency (equivalent to glass) and very low grade of auto-fluorescence
  • Standard microscope glass slide size (75.5 mm x 25.5 mm x 1.5 mm)
  • Cover lid thickness: 140 µm
  • 8 µm porous PET membrane

 

1x Open membrane organ-on-a-chip with mini Luer ports

Chip material Topas (COC)
Membrane material PET
Pore size (µm) 8
Lid thickness (µm) 140

Dimensions of the open membrane organ-on-a-chip

Click to read more information about ChipShop chips material properties.

Maurer, M., Gresnigt, M. S., Last, A., Wollny, T., Berlinghof, F., Pospich, R., ... & Mosig, A. S. (2019). A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies. Biomaterials,220, 119396. https://doi.org/10.1016/j.biomaterials.2019.119396

Raasch, M., Rennert, K., Jahn, T., Peters, S., Henkel, T., Huber, O., ... & Mosig, A. (2015). Microfluidically supported biochip design for culture of endothelial cell layers with improved perfusion conditions. Biofabrication, 7(1), 015013. doi:10.1088/1758-5090/7/1/015013

Rennert, K., Steinborn, S., Gröger, M., Ungerböck, B., Jank, A. M., Ehgartner, J., Nietzsche, S., Dinger, J., Kiehntopf, M., Funke, H., Peters, F. T., Lupp, A., Gärtner, C., Mayr, T., Bauer, M., Huber, O., & Mosig, A. S. (2015). A microfluidically perfused three dimensional human liver model. Biomaterials, 71, 119–131. https://doi.org/10.1016/j.biomaterials.2015.08.043

Payment Terms

You can either order and pay via credit card or invoice (through a purchase order). Request a quote easily by clicking on the "Request a Quote" button in the cart page.

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  • Fill in the required informations, then click on Submit Quote
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  • After receiving the quote, just send your purchase order at contact@darwin-microfluidics.com
  • Our team will complete your purchase and send you the invoice!

 

If you wish to pay in USD, GBP or AUD, please specify it in your PO. We can add the converted value in the required currency to the quote if requested.

 

Worldwide shipping

We ship worldwide from our warehouse in France.

Shipping charges are calculated based on the shipping country, and can be estimated from the cart page. Our shipping rates and times are:

  • France: GLS (1-2 business days), free shipping above 350€
  • Germany, Austria, Belgium, Denmark, Spain, Hungary, Italy, Luxembourg, Netherlands, Poland, Portugal, Czechia, Slovakia:
    • GLS (2-4 business days), free shipping above 350€
    • DHL Express (1-2 business days), reduced rate above 350€
  • Bulgaria, Croatia, Estonia, Finland, Ireland, Latvia, Lithuania, Romania, Slovenia, Sweden, Greece, Cyprus, Malta: DHL Express (1-2 business days), free shipping above 400€
  • United Kingdom: DHL Express (1-2 business days), free shipping above 400€
  • USA, Canada: DHL Express (1-3 business days), free shipping above 400€
  • Switzerland: DHL Express (1-2 days), free shipping above 450€
  • Other countries: DHL Express, shipping rates based on the destination, weight and dimensions

 

If you wish to use your own shipping account, we will charge a flat fee of 15€.

We reserve the right to apply a surcharge for parcels > 30 kg, palletized shipments, or packages with dimensions exceeding the maximum dimensions of our carriers.

Please note that our standard shipping incoterms are DAP (Delivered At Place), or EXW if using your own carrier.

Contact us if you have any questions!

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