Idealized Network for 3D co-culture - IMN3 radial chips

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Product SKU: SY-103007
Category: Microfluidic Chips, Microfluidic Organ-on-a-chip, Organ-on-a-chip Chips, SynVivo

These idealized co-culture designs are helpful tools in the organ-on-chip field to mimic cellular interactions in vitro and model several biological systems in 3D. This design is composed of a central chamber allowing 3D tissue culture surrounded by two outer channels, for the modeling of a wide range of cell-cell interactions.

Average lead time: 3-4 weeks

€450.00

These idealized co-culture designs are helpful tools in the organ-on-chip field to mimic cellular interactions in vitro and model several biological systems in 3D. This design is composed of a central chamber allowing 3D tissue culture surrounded by two outer channels, for the modeling of a wide range of cell-cell interactions.

The IMN3 Radial organ-on-chip design is made of a central 3D chamber filled with pillars (tissue chamber) and two outer channels. This side-by-side architecture enables the co-culture of different cell types with real-time visualization. These platforms allow the modeling of physiological shear stress and in vivo-like morphology of tissues.

The separation between the central and outer channels can be done with either slits or pillars and are available in several dimensions. In both cases, slits/pillars are spaced at regular intervals to create a barrier between the inner and outer chambers.

In the central chamber, pillars have a diameter of 25µm and are spaced by 50µm.

These designs can be used in a wide range of applications, for which specific product pages can be found in our bundle section.

3x IMN3 Radial chips

The chips have the format of a microscopic slide and are made of PDMS bonded to glass.

	SY-103002	SY-103003	SY-103004	SY-103006	SY-103007
Outer channel (µm)	200	200	200	100	100
Barrier type	Pillars	Pillars	Pillars	Slits	Slits
Barrier gap (µm)	3	8	8	50	50
Slit width Ws (µm)	-	-	-	2	2
Pillar height (µm)	3	3	3	-	-
Travel T (µm)	100	50	100	100	20
Depth (µm)	100	100	100	100	100

For all chips, the chamber is filled with pillars of 25 µm diameter and separated by a distance of 50 µm.

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